Non-invasive Transcranial Electrostimulation of the Brain Antinociceptive System as Method ofFES: an Overview

The presented overview is devoted to elaboration and study of effects of a new non-invasive method of transcranial electrostimulation (TES) of the brain antinociceptive system. In experiments the optimal electrical regimen and optimal head electrodes position were estimated, and the «quasiresonance» characteristics of the brain antinociceptive system were revealed. By means of different approaches it was proved that effects of this type of TES are homeostatic and resemble the effects of direct electrical stimulation of the antinociceptive system. The main TES curative effects were estimated in animal experimental pathological models. As a result of experimental studies special devices for TES were developed and recommendations for practical TES application as a method of treatment and prophylaxis were established, 18-year practical usage of new TES method according our recommendation for nonpharmaceutical treatment of several types of pathology in more than 300 hospitals and outpatient clinics in Russia demonstrated the high level of efficacy without side effects. The results were proved by double-blind passive and active placebo-control.